In London, the sideshow troupe of Doctor Parnassus promises the audience a journey to the "Imaginarium", an imaginary world commanded by the mind of Doctor Parnassus, where dreams come true. In the stories that Doctor Parnassus tells to his daughter Valentina, the midget Percy, and his assistant Anton, he claims to have lived for more than one thousand years; However, when he fell in love with a mortal woman, he made a deal with the devil (Mr. Nick), trading his immortality for youth. As part of the bargain, he promised his son or daughter to Mr. Nick on their sixteenth birthday. Valentina is now almost to the doomed age and Doctor Parnassus makes a new bet with Mr. Nick, whoever seduces five souls in the Imaginarium will have Valentina as a prize. Meanwhile the troupe rescues Tony, a young man that was hanged on a bridge by the Russians. Tony was chased until he finds and joins the group. Tony and Valentina fall in love with each other and the jealous Anton discovers that his competition may be a liar.

Flint Lockwood thinks he's a genius. But none of the things he invented are things that make sense or are useful. However, he has the support of his mother but when she dies, he's left alone with his father who thinks he should give it up. When the community that he lives in is in an economic crisis because their primary source of income, a sardine cannery, was shut down, Flint decides to try his latest invention, a machine that can turn water into food. But something goes wrong and the machine ends up in the atmosphere. Later it starts raining food. The shifty mayor tries to use this as a way to help their community, but when Flint senses something wrong with the machine, the mayor convinces him to ignore it. However, as Flint predicts, chaos ensues.

A young boy named Max has an active imagination, and he will throw fits if others don't go along with what he wants. Max - following an incident with Claire (his sister) and her friends, and following a tantrum which he throws as a result of his Mother paying more attention to her boyfriend than to him - runs away from home. Wearing his wolf costume at the time, Max not only runs away physically, but runs toward a world in his imagination. This world, an ocean away, is inhabited by large wild beasts, including one named Carol who is much like Max himself in temperament. Instead of eating Max like they normally would with creatures of his type, the wild things befriend Max after he proclaims himself a king who can magically solve all their problems.

In a car race in McKinley Speedway, twenty-something Nick has a premonition of a deadly car crash with many casualties in the audience and convinces his girlfriend Lori and his friends Hunt and Janet to leave the place. They are followed by the security guard; a racist guy; a mother with her children and a mechanic, that are saved from death. When the racist guy and the mother die in mysterious and creepy incidents, Nick and Lori research and find many similar cases in Internet. They try to lure The Reaper to break the chain of deadly events and survive, but destiny does not help them.

Sam Reide has the ability of traveling to the past and works with the police department solving unresolved crimes, witnessing the events with the support of his sister, Jenna Rei